RightMed comprehensive test

The RightMed® comprehensive test is a provider-ordered pharmacogenomic test that analyzes a patient’s DNA to determine how he or she may respond to hundreds of medications used to treat and manage many medical conditions. This information, provided in both static and interactive reports, may help providers make more informed prescription decisions, protect patients from adverse drug reactions and drug ineffectiveness, and reduce healthcare costs.

Test details

pill bottle

Medications

The RightMed comprehensive test covers hundreds of commonly prescribed medications, including omeprazole (Prilosec), simvastatin (Zocor), citalopram (Celexa), clopidogrel (Plavix), warfarin (Coumadin), codeine, alprazolam (Xanax), phenytoin (Dilantin), metoprolol (Lopressor), plus many more.


View complete medication list >

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Medical conditions

The RightMed comprehensive test covers medications used for many medical conditions.

    • Acute migraine
    • ADHD
    • Allergies
    • Alzheimer's disease
    • Anticoagulation
    • Antiplatelet therapy
    • Anxiety
    • Arrhythmias
    • Bacterial infection
    • Benign prostatic
      hyperplasia
    • Cancer
    • Chronic hepatitis C
    • Depression
    • Diabetes
    • Dyslipidemia
    • Fungal infection
    • Gastroesophageal
      reflux disease
    • Gout
    • HIV infection
    • Hypertension
    • Immunosuppression
    • Migraine prophylaxis
    • Overactive bladder
    • Pain
    • Parkinson's disease
    • Psychosis
    • Rheumatoid arthritis
    • Seizures
    • Sleep disorders
    • Smoking cessation

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Genes

The RightMed comprehensive test analyzes genes involved in drug metabolism, drug targets, drug receptors, and drug transporters. Analysis is provided for genes that have been shown, based on OneOme's rigorous research and standards for inclusion, to affect how a patient responds to many commonly prescribed medications.


CYP1A2 *1C, *1D, *1E, *1F, *1J, *1K, *1L, *1V, *1W
rs12720461

rs2069514

rs2069526

rs35694136

rs762551
NM_000761.4:c.-10+113C>T

NG_008431.2:g.28338G>A

NM_000761.4:c.-10+103T>G

NM_000761.4:c.-1635delT

NM_000761.4:c.-9-154C>A
CYP2B6 *4, *5, *6, *7, *9, *16, *18
rs2279343

rs28399499

rs3211371

rs3745274
NM_000767.4:c.785A>G

NM_000767.4:c.983T>C

NM_000767.4:c.1459C>T

NM_000767.4:c.516G>T
CYP2C9 *2, *3, *4, *5, *6, *8, *11, *18
rs1057910

rs1057911

rs1799853

rs28371685

rs28371686

rs56165452

rs7900194

rs9332131
NM_000771.3:c.1075A>C

NM_000771.3:c.1425A>T

NM_000771.3:c.430C>T

NM_000771.3:c.1003C>T

NM_000771.3:c.1080C>G

NM_000771.3:c.1076T>C

NM_000771.3:c.449G>A

NM_000771.3:c.817delA
CYP2C19 *2, *3, *4, *4B, *10, *17
rs12248560

rs28399504

rs4244285

rs4986893

rs6413438
NM_000769.2:c.-806C>T

NM_000769.2:c.1A>G

NM_000769.2:c.681G>A

NM_000769.2:c.636G>A

NM_000769.2:c.680C>T
CYP2D6 *2A, *2, *3, *4, *4N, *4M, *5, *6, *6C, *7, *8, *9, *10, *11, *12, *13, *14A, *14B, *15, *17, *18, *19, *29, *31, *34, *35, *36, *39, *41, *42, *63, *64, *68, *69, *70, *91, *109
hCV32407220 (rs765776661)

rs1065852

rs1080985

rs1135840

rs16947

rs201377835

rs267608319

rs28371706

rs28371725

rs35742686

rs3892097

rs5030655

rs5030656

rs5030862

rs5030865

rs5030867

rs59421388

rs72549346

rs72549353

rs769258

rs774671100
NM_000106.5:c.1411_1412insTGCCCACTG

NM_000106.5:c.100C>T

NM_000106.5:c.-1584C>G

NM_000106.5:c.1457G>C

NM_000106.5:c.886C>T

NM_000106.5:c.181-1G>C

NM_000106.5:c.1319G>A

NM_000106.5:c.320C>T

NM_000106.5:c.985+39G>A

NM_000106.5:c.775delA

NM_000106.5:c.506-1G>A

NM_000106.5:c.454delT

NM_000106.5:c.841_843delAAG

NM_000106.5:c.124G>A

NM_000106.5:c.505G>A

NM_000106.5:c.971A>C

NM_000106.5:c.1012G>A

NM_000106.5:c.1088_1089insGT

NM_000106.5:c.765_768delAACT

NM_000106.5:c.31G>A

NM_000106.5:c.137_138insT
CYP3A4 *1B, *22
rs2740574

rs35599367
NM_017460.5:c.-392G>A

NM_017460.5:c.522-191C>T
CYP3A5 *3, *6, *7
rs10264272

rs41303343

rs776746
NM_000777.4:c.624G>A

NM_000777.4:c.1035_1036insT

NM_000777.4:c.219-237G>A
COMT Val158Met
rs4680 NM_000754.3:c.472G>A
DPYD *2A (1905+1G>A, IVS14+1G>A), Asp949Val, *13
rs3918290

rs55886062

rs67376798
NM_000110.3:c.1905+1G>A

NM_000110.3:c.1679T>G

NM_000110.3:c.2846A>T
DRD2 Promoter variant -241A>G
rs1799978 NM_000795.3:c.-585A>G
F2 20210G>A
rs1799963 NM_000506.4:c.*97G>A
F5 Arg534Gln (Leiden, 1691G>A)
rs6025 NM_000130.4:c.1601G>A
GRIK4 Non-coding (intronic) T>C variant
rs1954787 NM_001282470.2:c.83-10039T>C
HTR2A Intron 2, T>C variant
rs7997012 NM_000621.4:c.614-2211T>C
HTR2C Promoter variant -759C>T
rs3813929 NM_000868.3:c.-759C>T
IL28B (IFNL4) Non-coding (intronic) C>T variant
rs12979860 NM_001276254.2:c.151-152G>A
NUDT15 Arg139Cys
rs116855232 NM_018283.3:c.415C>T
OPRM1 Asn40Asp; 118A>G
rs1799971 NM_000914.4:c.118A>G
SLC6A4 c.-1810A>G; -1791_-1749del43
rs25531

rs774676466
NM_001045.5:c-1936A>G

NM_001045.5:c.-1917_-1875del43
SLCO1B1 *5, *17, *21
rs4149015

rs4149056
NM_006446.4:c.-910G>A

NM_006446.4:c.521T>C
TPMT *2, *3A, *3B, *3C, *4
rs1142345

rs1800460

rs1800462

rs1800584
NM_000367.3:c.719A>G

NM_000367.3:c.460G>A

NM_000367.3:c.238G>C

NM_000367.3:c.626-1G>A
UGT1A1 *6, *28 (TA7)
rs1976391

rs4148323
NM_001072.3:c.862-9697A>G

NM_001072.3:c.862-6536G>A
VKORC1 Promoter variant -1639G>A
rs9923231 NM_001311311.1:c.-1639G>A

RightMed comprehensive test report


With the RightMed comprehensive test, providers receive a clinically actionable report that categorizes drugs into a simple, easy-to-read format:

  • high risk icon
    MAJOR
    GENE-DRUG
       INTERACTION   

  • medium risk icon
    MODERATE
    GENE-DRUG
       INTERACTION   

  • low risk icon
    MINIMAL
    GENE-DRUG
       INTERACTION   

Providers may use the information from the test report to guide medication and dosage decisions based on the patient's DNA, the drug binning, and clinical annotations.

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The RightMed Advisor

Providers also have access to the RIGHTMED ADVISOR, an interactive tool to help providers quickly and easily interpret test results, explore more information about the hundreds of drugs in OneOme’s database, evaluate drug-to-drug interactions, and view curated medication alternatives.

Providers can generate custom reports by selecting the medications they would like displayed in a RightMed Advisor custom report, which helps providers get more in-depth information and focus on the drugs that matter the most for each patient.


Reports

In addition to the RightMed comprehensive test report, providers can generate additional reports, including RightMed Advisor reports and specialty reports.

The RightMed Advisor reports are built by the provider selecting which medications they would like highlighted, giving them the power to build their own in-depth, customized report.

Specialty reports include a subset of medications selected and classified by OneOme’s clinical team.


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Sample collection and processing

The RightMed comprehensive test includes DNA collection through either buccal (cheek) swab or blood. DNA samples are processed at OneOme’s in-house CLIA/CAP-accredited laboratory.


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If you are a patient, get started by DOWNLOADING THE PATIENT TOOLKIT, which contains information on how to talk to your doctor about the test. This test is not right for everyone. Consult your doctor to see if this test is right for you.