Why OneOme?

Cost-effective, comprehensive, personalized pharmacogenomic analysis — integrated into patients' everyday clinical care

Addressing the whole patient

The OneOme RightMed® pharmacogenomic test allows providers to make decisions across more than 340 medications for more than 20 medical indications.

The OneOme RightMed PGx interactive drug report tool allows providers to explore, filter, and generate custom reports with annotations and drug-drug interactions based on specific criteria or medical indications.



Curated, credible data

At OneOme, we continually curate our clinical PGx database, only adding drugs characterized by high levels of evidence from FDA drug labeling and the Clinical Pharmacogenetics Implementation Consortium (CPIC)1,2

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THE ONEOME STANDARD

The data is curated by a team of scientists, physicians, and pharmacists and takes into account clinical data and literature on the metabolism of each drug. Only pharmacogenomic data meeting adequate levels of evidence are included in the OneOme database. Levels of evidence refer to the strength of the scientific data supporting the association between a drug and a pharmacogene. This allows the OneOme team to establish a multi-gene profile of the drug. Lower levels of evidence may exist for drugs and genes, but are not considered strong enough for inclusion in OneOme reports.

The genes included in the OneOme analysis might impact other drugs that are not included on the RightMed PGx test because of insufficient clinical evidence. The absence of a drug in the OneOme report does not imply that there is no interaction between the drug and the genes analyzed in this test.

VIEW GENES AND MEDICAL CONDITIONS COVERED BY THE ONEOME RightMed® TEST >

Actionable, at-a-glance report

Designed to be useful and clear in real workflows, the OneOme RightMed PGx report informs targeted, timely, evidence-based decisions. Providers can easily identify optimal drug therapy for individual patients, making personalized treatment decisions.

The individual genetic results are analyzed by OneOme's proprietary algorithm, which takes into account the cumulative effect from each of the genotypes to provide a reproducible and consistent interpretation of pharmacogenomic data.

Based on the algorithmic analysis, the OneOme RightMed report categorizes drugs into a simple, scannable format:

  • Check icon
    use as
    directed
  • Warning icon
    use with
    caution
  • Danger icon
    use with
    great caution

Custom annotations and drug-drug interactions

Drug interactions can cause unwanted side effects, reduce the effectiveness of some medicines, and increase the action of others. The OneOme RightMed PGx interactive, custom drug report tool allows providers to:

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      filter and select
      medications based on
      medical condition and/or
      patient medication history

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      search all medications
      in the database

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      view detailed information
      about any medication

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      identify alternative
      medications

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      explore drug-drug
      interactions

This information can help a provider determine if currently prescribed medications may cause adverse interactions. Some drug-drug interactions can occur when there is induction or inhibition within the same family of drug metabolism enzymes.

  • Inducer Icon
      Inducers
      Inducers increase the rate of metabolism of another drug requiring the dosage to be adjusted to maintain effectiveness.
  • Inhibitor Icon
      Inhibitors
      Inhibitors reduce the metabolism rate and can cause the drug level to rise, potentially leading to harmful or adverse effects.

View Cytochrome P450 (CYP) inhibitors and inducers >

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