Evidence-based pharmacogenomics
Pharmacogenomic (PGx) testing analyzes a patient’s DNA and provides genetic information to help providers make more informed prescribing decisions for that patient. The RightMed Test is a PGx test that offers comprehensive coverage backed by rigorous curation of high-level, scientific evidence to give providers and their patients confidence in test results.
Comprehensive
The RightMed Test covers 27 genes that may impact how a patient responds to certain medications used to treat various conditions including psychiatric conditions, cancer, cardiovascular disease, pain, and more.
Evidence-based
The RightMed Test’s gene coverage has been selectively curated by a group of clinical pharmacists and experts using OneOme’s rigorous standards for pharmacogenomic evidence. Each sample is analyzed at OneOme’s CLIA-certified, CAP-accredited in-house laboratory.
The RightMed Gene Report
RightMed Test results are presented in the RightMed Gene Report, which includes the genotype, corresponding phenotype and summary, as well as laboratory methods employed, including variants tested.
Clinical uses
The RightMed Test offers valuable insights for providers who care for patients with a variety of health conditions and needs.
These include (but aren't limited to):
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Psychiatric conditions
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Cancer and supportive care
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Acute or chronic pain
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Complex polypharmacy
Genes covered
The test analyzes more than 100 variants in 27 genes
| Gene | Alleles |
|---|---|
| CYP1A2 | *1C, *1D, *1E, *1F, *1J, *1K, *1L, *1V, *1W |
| CYP2B6 | *4, *5, *6, *7, *9, *16, *18 |
| CYP2C Cluster | G/A |
| CYP2C9 | *2, *3, *4, *5, *6, *8, *11 |
| CYP2C19 | *2, *3, *4, *4B, *10, *17 |
| CYP2D6 | *2, *2A, *3, *4, *4M, *4N, *5, *6, *6C, *7, *8, *9, *10, *11, *12, *13, *14, *15, *17, *18, *19, *20, *29, *31, *34, *35, *36, *39, *41, *42, *59, *63, *64, *68, *69, *70, *91, *109, *114, allele duplications and multiplications |
| CYP3A4 | *1B, *22 |
| CYP3A5 | *3, *6, *7 |
| CYP4F2 | *3 |
| COMT | VAL158MET |
| DPYD | *2A (1905+1G>A, IVS14+1G>A), ASP949VAL, *13 |
| DRD2 | PROMOTER VARIANT -241A>G |
| F2 | 20210G>A |
| F5 | ARG534GLN (LEIDEN, 1691G>A) |
| GRIK4 | NON-CODING (INTRONIC) T>C VARIANT |
| HLA-A | HLA-A*31:01 |
| HLA-B | HLA-B*15:02, HLA-B*57:01, HLA-B*58:01 |
| HTR2A | INTRON 2, T>C VARIANT |
| HTR2C | PROMOTER VARIANT -759C>T |
| IL28B (IFNL4) | NON-CODING (INTRONIC) C>T VARIANT |
| MTHFR* | 677C>T; 1298A>C |
| NUDT15 | ARG139CYS |
| OPRM1 | ASN40ASP; 118A>G |
| SLC6A4 | C.-1810A>G; -1791_-1749DEL43 |
| SLCO1B1 | *5, *15, *17, *21 |
| TPMT | *2, *3A, *3B, *3C, *4 |
| UGT1A1 | *6, *28 (TA7) |
| VKORC1 | PROMOTER VARIANT -1639G>A |
NOTE: The test does not detect all known and unknown variations in the gene(s) tested. For drug metabolizing enzyme, the absence of a detectable variant (designated as *1) does not rule out the presence of other variants not tested.
*MTHFR is available for providers to order as an optional, complimentary add-on to the RightMed Test. MTHFR is not available to patients who purchase the test online (ordered through the independent physician network).
Learn more about RightMed
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For health systems
Learn more about the value of adding PGx to precision medicine programs, RightMed Solution configurations for institutions, and how to get started. Plus, get access to informative resources to help develop your PGx program.
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For payers, PBMS, & employers
Learn more about the value of OneOme’s RightMed for Populations solution, how it works, and how to get started. Plus, access informative resources to help you leverage PGx in your populations.
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For providers & pharmacists
Learn more about the benefits of the test and how it works (from ordering to interpretation). Plus, get access to educational resources to help you incorporate PGx to your patient care.
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For patients
Learn how the test works, the potential benefits of the test, and how to find a provider who can order the test for you.
Have questions about the RightMed Test?
Dedicated experts are available to answer your questions. Speak with a client service representative today.